The HANABI-L 2.0 Automated Lymphocyte Isolator System and the HANABI-CI 4.0 Automated Cell Isolator System are designed for today’s laboratories that require increased throughput of lymphocyte isolation for higher productivity in providing consistent, high-quality sample preparation.

• The HANABI-CI 4.0 Automated Cell Isolator System is capable of processing single patient, 15 mL to 120 mL whole blood samples in 1.5 hours.
• The HANABI-L 2.0 Automated Lymphocyte Isolator System is capable of processing batches of 24 samples and features a negative pressure cabinet and ultraviolet exposure

Lymphocytes

Lymphocytes are a type of white blood cell that are part of the immune system.

Lymphocytes have round or oval nuclei and generally are 8 to 12 microns in diameter. A rapid increase in the number of lymphocytes present in the blood (lymphocytosis) often indicates the presence of a pathological intrusion; in severe cases, it may be leukemia (blood cancer), although in most cases this relates to a simple inflammation. Lymphocytes are divided into two classes, B Cells and T Cells. B cells produce antibodies used to attack invading bacteria, viruses, and toxins, whereas T cells destroy the body’s own cells that have themselves been taken over by viruses or become cancerous.

Blood cell development. A blood stem cell goes through several steps to become a red blood cell, platelet, or white blood cell.
(Source: NIH – National Human Genome Research Institute)

The Action of Lymphocytes

The acquired immune system triggers a response when an innate immune system response has not been activated.

The life of lymphocytes is short, like other white blood cells. Some remain in the body for years, however, providing future lymphocytes with a “memory” against those external agents that have previously attacked the body. This ensures a more efficient immune response in years to come.

Immunotherapy
According the National Cancer Institute, Immunotherapy is a type of cancer treatment that helps your immune system fight cancer. The immune system helps your body fight infections and other diseases. It is made up of white blood cells and organs and tissues of the lymph system.
(Source: https://www.cancer.gov/about-cancer/treatment/types/immunotherapy)

Lymphocytes are the only blood cells which can be transformed into actively proliferating cells. They originate from lymphatic tissue throughout the body. Lymphocytes collected from blood have been in frequent use in the field of immunology.

Cell Isolation Systems